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Printable Version Prometh and Codeine

Active Ingredients: Promethazine and Codeine
Other Names: Codeine Phosphate and Promethazine Hydrochloride Syrup, Codeine and Promethazine Syrup, Prometh with Codeine Syrup, Promethazine with Codeine Syrup
Rx Status: Available by prescription only
Generic Available: Yes
Product Images & Descriptions:

What is/are Prometh and Codeine?
What should I tell my health care providers before I take this medicine?
How should I use this medicine?
What if I miss a dose?
What may interact with this medicine?
What side effects may I notice from this medicine?
What should I watch for while using this medicine?
Where should I keep this medicine?

What is/are Prometh and Codeine? (Back to top)
CODEINE; PROMETHAZINE is a cough suppressant and an antihistamine. It helps to stop or reduce coughing due to colds or allergies. This medicine will not treat an infection. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.


What should I tell my health care providers before I take this medicine? (Back to top)
They need to know if you have any of these conditions:

  • asthma
  • glaucoma
  • head injury
  • difficulty passing urine
  • other chronic illness
  • seizure disorder
  • sleep apnea
  • stomach ulcer
  • an allergic or unusual reaction to codeine, promethazine, phenothiazines, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine? (Back to top)
Take this medicine by mouth with a full glass of water. Follow the directions on the prescription label. Use a specially marked spoon or container to measure your medicine. Ask your pharmacist if you do not have one. Household spoons are not accurate. Take this medicine with food or milk if it upsets your stomach. Take your doses at regular times. Do not take more medicine than directed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed. While this drug may be prescribed for patients as young as 16 years old for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

Note: This medicine is only for you. Do not share this medicine with others.


What if I miss a dose? (Back to top)
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.


What may interact with this medicine? (Back to top)
Do not take this medicine with any of the following:

  • disopyramide
  • risperidone

This medicine may also interact with the following:
  • any alcohol containing product
  • barbiturate medicines for inducing sleep or treating seizures
  • medicines for colds or allergies
  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
  • some medicines for depression, anxiety, or other mental disturbances
  • some medicines for pain
  • sleeping pills or tranquilizers

This list may not describe all possible interactions. Give your health care providers a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.


What side effects may I notice from this medicine? (Back to top)
Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • blurred vision
  • breathing problems
  • dark urine
  • feeling faint or lightheaded
  • hallucinations
  • irregular heartbeat
  • muscle twitches or tremors
  • seizures
  • trouble passing urine
  • unusual bleeding or bruising
  • unusually weak or tired
  • yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
  • constipation
  • dry eyes
  • headache
  • stomach upset, nausea

This list may not describe all possible side effects.


What should I watch for while using this medicine? (Back to top)
Tell your doctor or health care professional if your symptoms do not improve or if they get worse. If you have a high fever, skin rash, or headache, see your health care professional.

If you are diabetic, check your blood sugar levels regularly.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.

Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.

This medicine may cause dry eyes and blurred vision. If you wear contact lenses you may feel some discomfort. Lubricating drops may help. See your eye doctor if the problem does not go away or is severe.


Where should I keep this medicine? (Back to top)
Keep out of the reach of children. This medicine can be abused. Keep your medicine in a safe place to protect it from theft. Do not share this medicine with anyone. Selling or giving away this medicine is dangerous and against the law.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light. Throw away any unused medicine after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.


Last Updated:August 11, 2008

COPYRIGHT© Gold Standard, An Elsevier Company


Note: The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist, or other healthcare professional. It should not be construed to indicate that the use of the product is safe, appropriate, or effective for you. Consult your healthcare professional before taking the product.

  Additional Information

  Check Drug Interactions with Prometh and Codeine

  Test Yourself! If you currently take Prometh and Codeine, do you know everything that you need to know?

  Make your own printable Medication / Emergency Contact Card



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